La Plata, MO is a city located in Macon County, Missouri and has a land area of 134.94 square miles (349.49 km2). The water area for the city is 0.38 square miles or 0.98 km2. There is one unique zip code in La Plata, Missouri and it is 63549. The area code(s) for La Plata is 660.
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